This service is held on a Tuesday each year, so this year it is taking place on the eve of the Week of Prayer which runs from January 18-25.
As is the turn of the Roman Catholic Cathedral to host the service, Church of Ireland Primate Archbishop Richard Clarke chooses the preacher, and he has asked the Bishop of Clogher, the Rt Rev John McDowell.
The service is repeated in Armagh on Wednesday January 18 with the same preacher.
The Belfast service will be themed: ‘Reconciliation – The Love of Christ compels us,’ based on the text 2 Corinthians 5: 14-20.
Church leaders who will be present include the Church of Ireland Bishop of Down and Dromore, the Rt Rev Harold Miller; Dr John Dunlop (representing the Moderator of the Presbyterian Church); Bishop Anthony Farquar (Roman Catholic) and the Rev Bill Mullalley (Methodist President).
The Dean of Belfast, the Very Rev John Mann (St Anne’s Cathedral), and the new Administrator of St Peter’s Cathedral, Fr Martin Graham, will take part in the service and the joint choirs of St Peter’s Cathedral and St Anne’s Cathedral will lead the singing and provide two anthems.
The service begins at 7pm on Tuesday January 17 and all are welcome.